Vitamin D Overdose

To counter fears of overdosing, it should be remembered that much higher doses were used in medicine in the past. In the 1970s, every newborn was given a rickets prophylaxis syringe containing 200,000 units. Thus infants were given up to 60,000 units per 2 pounds/1 kilogram of body weight. With the initial vitamin D therapy, the single dose is a maximum of 7000 units per kilogram of body weight, even in extreme deficiency. That is only one-eighth of the infant dose that has been common for decades.

People who expose their entire body to UVB radiation from the sun, such as pool attendants in summer and members of tropical indigenous peoples, remain below 100 ng/ml. In individual cases, values ​​of 105 ng/ml were documented. With a vitamin D level of 100 ng/ml, there is no danger.

When Can A Vitamin D Overdose Occur?

Even a vitamin D level of up to 150 ng/ml appears to be harmless. Only devaluing from 150 to 200 ng/ml are individual cases with increased calcium in the serum described in the specialist literature. To reach the critical threshold of 150 ng/ml, a patient weighing 70 kg must take around 75 capsules of 20,000 units each at once (a total of 1,500,000 units).

There is a real danger at a vitamin D level of over 300 ng/ml, as suggested by individual cases that have been reported in the specialist literature. A limit value of 100 ng/ml offers a higher safety factor, far more than with conventional drugs.

A vitamin D overdose can only result from a miscalculation or if the patient does not adhere to the dose recommendations.

In practice, an elderly patient was noticed because he asked for a prescription shortly after starting the vitamin D therapy. When asked, it turned out that he had ignored the written instructions. After the initial therapy with 15 capsules (300,000 units), he took another 35 capsules, one per day. His vitamin D level had only risen to 103 ng/ml despite a daily dose of 20,000 units, as a control measurement showed.

The calcium level was normal and the patient was free from symptoms. Further therapy was withheld until the vitamin D level had fallen to the target value and then the maintenance dose was restarted.

After the unauthorized ingestion of 50 capsules (20,000 units per capsule) in 2 weeks (4 capsules per day), a vitamin D level of 126 ng/ml was reached. The patient’s condition was normal and their calcium level was normal. Even at this high dose, there was not really an overdose of vitamin D.

The fear that taking vitamin D supplements would lead to increased kidney stones has proven to be unfounded.

At this point, an addition should be added. After the initial therapy, the calcium level regularly rises to the normal upper range. Many laboratories rate values ​​above 2.60 mmol/l as abnormally elevated. However, international studies only consider values ​​above 2.75 mmol/l as problematic “hypercalcemia” (abnormally increased calcium levels in the blood).

A research group from Paris sees no danger as long as the calcium level remains below 3.00 mmol/l. There are no sources that describe a danger for the range from 2.60 to 3.00 mmol/l. The typical upper limit of 2.60 mmol/l only reflects the nationwide vitamin D deficiency consequences.

The population, which is largely ill, pulls down the range for vitamin D and calcium. Therefore, it is therefore important to normalize the vitamin D level and not be irritated by “increased” calcium values ​​as long as these remain below 3.00 mmol/l. This means that there is no risk of “calcification” of the blood vessels. Instead, the lack of vitamin D is a risk factor for atherosclerosis.

The vitamin D level should not be viewed in isolation. With severe vitamin D deficiency, most people get calcification of the arterial walls with increasing age, while decreasing bone mass. The main reasons for this are: lack of vitamin K2 and magnesium and overload with calcium (from supplements, milk, cheese, yogurt, quark). There is more of a risk of chronic calcium overload, even with low vitamin D levels.

The vitamin D therapy is safe and harmless, even if several 100,000 units (unnecessary) are taken during the initial therapy!

It is almost impossible to overdose on vitamin D.

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